Extent of, and factors associated with, delay to hospital presentation in patients with Acute Coronary disease (the GRACE registry)
Identifieur interne : 00B728 ( Main/Exploration ); précédent : 00B727; suivant : 00B729Extent of, and factors associated with, delay to hospital presentation in patients with Acute Coronary disease (the GRACE registry)
Auteurs : Robert J. Goldberg [États-Unis, France, Pologne, Australie, Brésil, Canada] ; Philippe Gabriel Steg ; Immad Sadiq ; Christopher B. Granger ; Elizabeth A. Jackson ; Andrzej Budaj ; David Brieger ; Alvaro Avezum ; Shaun GoodmanSource :
- The American journal of cardiology [ 0002-9149 ] ; 2002.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Our primary study aim was to examine extent of, and factors associated with, delay in seeking medical care in a large multinational registry of patients with acute myocardial infarction (AMI) and unstable angina pectoris. A secondary goal was to examine the relation between duration of prehospital delay and receipt and timing of coronary reperfusion strategies. Investigators from 14 countries are participating in the Global Registry of Acute Coronary Events (GRACE) project. The study sample consisted of 3,693 patients with ST-segment elevation AMI, 2,935 with non-ST-segment elevation AMI, and 3,954 patients with unstable angina hospitalized between 1999 and 2001. The average and median delay times were longest in patients with non-ST-segment elevation AMI (6.1 and 3.0 hours, respectively) followed by patients with unstable angina (5.6 and 3.0 hours) and those with ST-segment elevation AMI (4.7 and 2.3 hours). Approximately 41% of patients with ST-segment elevation AMI presented to the 94 study hospitals within 2 hours of the onset of acute coronary symptoms; this compared with approximately one third of patients with non-ST-segment elevation AMI and unstable angina. Several demographic and clinical characteristics were associated with prehospital delay. In patients with ST-segment elevation AMI, duration of prehospital delay was inversely related to the receipt of thrombolytic therapy, but was inconsistently related to the use of percutaneous coronary interventions. The results of this study demonstrate that a large proportion of patients continue to exhibit prolonged delay in seeking medical care after the onset of acute coronary symptoms and remain in need of targeted educational efforts to reduce extent of delay.
Affiliations:
- Australie, Brésil, Canada, France, Pologne, États-Unis
- Caroline du Nord, Massachusetts, Ontario, État de São Paulo, Île-de-France
- Paris, São Paulo, Toronto
- Université de Toronto
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 005812
- to stream PascalFrancis, to step Curation: 000927
- to stream PascalFrancis, to step Checkpoint: 005429
- to stream Main, to step Merge: 00C550
- to stream Main, to step Curation: 00B728
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Extent of, and factors associated with, delay to hospital presentation in patients with Acute Coronary disease (the GRACE registry)</title><author><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Service de Cardiologie, Hôpital Bichat</s1><s2>Paris</s2><s3>FRA</s3></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Duke University Medical Center</s1><s2>Durham, North Carolina</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Grochowski Hospital</s1><s2>Warsaw</s2><s3>POL</s3></inist:fA14><country>Pologne</country><wicri:noRegion>Grochowski Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Concord Hospital</s1><s2>Sydney, New South Wales</s2><s3>AUS</s3></inist:fA14><country>Australie</country><wicri:noRegion>Concord Hospital</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>CTI-A Hospital Albert Einstein</s1><s2>São Paulo</s2><s3>BRA</s3></inist:fA14><country>Brésil</country><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>St Michaels Hospital, University of Toronto</s1><s2>Toronto, Ontario</s2><s3>CAN</s3></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name></author><author><name sortKey="Sadiq, Immad" sort="Sadiq, Immad" uniqKey="Sadiq I" first="Immad" last="Sadiq">Immad Sadiq</name></author><author><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B." last="Granger">Christopher B. Granger</name></author><author><name sortKey="Jackson, Elizabeth A" sort="Jackson, Elizabeth A" uniqKey="Jackson E" first="Elizabeth A." last="Jackson">Elizabeth A. Jackson</name></author><author><name sortKey="Budaj, Andrzej" sort="Budaj, Andrzej" uniqKey="Budaj A" first="Andrzej" last="Budaj">Andrzej Budaj</name></author><author><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name></author><author><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name></author><author><name sortKey="Goodman, Shaun" sort="Goodman, Shaun" uniqKey="Goodman S" first="Shaun" last="Goodman">Shaun Goodman</name></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">02-0226463</idno><date when="2002">2002</date><idno type="stanalyst">PASCAL 02-0226463 INIST</idno><idno type="RBID">Pascal:02-0226463</idno><idno type="wicri:Area/PascalFrancis/Corpus">005812</idno><idno type="wicri:Area/PascalFrancis/Curation">000927</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">005429</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">005429</idno><idno type="wicri:doubleKey">0002-9149:2002:Goldberg R:extent:of:and</idno><idno type="wicri:Area/Main/Merge">00C550</idno><idno type="wicri:Area/Main/Curation">00B728</idno><idno type="wicri:Area/Main/Exploration">00B728</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Extent of, and factors associated with, delay to hospital presentation in patients with Acute Coronary disease (the GRACE registry)</title><author><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Service de Cardiologie, Hôpital Bichat</s1><s2>Paris</s2><s3>FRA</s3></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Duke University Medical Center</s1><s2>Durham, North Carolina</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Grochowski Hospital</s1><s2>Warsaw</s2><s3>POL</s3></inist:fA14><country>Pologne</country><wicri:noRegion>Grochowski Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Concord Hospital</s1><s2>Sydney, New South Wales</s2><s3>AUS</s3></inist:fA14><country>Australie</country><wicri:noRegion>Concord Hospital</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>CTI-A Hospital Albert Einstein</s1><s2>São Paulo</s2><s3>BRA</s3></inist:fA14><country>Brésil</country><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="07"><s1>St Michaels Hospital, University of Toronto</s1><s2>Toronto, Ontario</s2><s3>CAN</s3></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name></author><author><name sortKey="Sadiq, Immad" sort="Sadiq, Immad" uniqKey="Sadiq I" first="Immad" last="Sadiq">Immad Sadiq</name></author><author><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B." last="Granger">Christopher B. Granger</name></author><author><name sortKey="Jackson, Elizabeth A" sort="Jackson, Elizabeth A" uniqKey="Jackson E" first="Elizabeth A." last="Jackson">Elizabeth A. Jackson</name></author><author><name sortKey="Budaj, Andrzej" sort="Budaj, Andrzej" uniqKey="Budaj A" first="Andrzej" last="Budaj">Andrzej Budaj</name></author><author><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name></author><author><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name></author><author><name sortKey="Goodman, Shaun" sort="Goodman, Shaun" uniqKey="Goodman S" first="Shaun" last="Goodman">Shaun Goodman</name></author></analytic><series><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno><imprint><date when="2002">2002</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Care</term><term>Exploration</term><term>Hospital admission</term><term>Human</term><term>Infarct</term><term>Myocardium</term><term>Reperfusion</term><term>Risk factor</term><term>Timing</term><term>Treatment</term><term>Variant angina</term><term>Waiting time</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Angor instable</term><term>Homme</term><term>Admission hôpital</term><term>Infarctus</term><term>Myocarde</term><term>Temps attente</term><term>Exploration</term><term>Reperfusion</term><term>Traitement</term><term>Timing</term><term>Soin</term><term>Facteur risque</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Our primary study aim was to examine extent of, and factors associated with, delay in seeking medical care in a large multinational registry of patients with acute myocardial infarction (AMI) and unstable angina pectoris. A secondary goal was to examine the relation between duration of prehospital delay and receipt and timing of coronary reperfusion strategies. Investigators from 14 countries are participating in the Global Registry of Acute Coronary Events (GRACE) project. The study sample consisted of 3,693 patients with ST-segment elevation AMI, 2,935 with non-ST-segment elevation AMI, and 3,954 patients with unstable angina hospitalized between 1999 and 2001. The average and median delay times were longest in patients with non-ST-segment elevation AMI (6.1 and 3.0 hours, respectively) followed by patients with unstable angina (5.6 and 3.0 hours) and those with ST-segment elevation AMI (4.7 and 2.3 hours). Approximately 41% of patients with ST-segment elevation AMI presented to the 94 study hospitals within 2 hours of the onset of acute coronary symptoms; this compared with approximately one third of patients with non-ST-segment elevation AMI and unstable angina. Several demographic and clinical characteristics were associated with prehospital delay. In patients with ST-segment elevation AMI, duration of prehospital delay was inversely related to the receipt of thrombolytic therapy, but was inconsistently related to the use of percutaneous coronary interventions. The results of this study demonstrate that a large proportion of patients continue to exhibit prolonged delay in seeking medical care after the onset of acute coronary symptoms and remain in need of targeted educational efforts to reduce extent of delay.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Brésil</li><li>Canada</li><li>France</li><li>Pologne</li><li>États-Unis</li></country><region><li>Caroline du Nord</li><li>Massachusetts</li><li>Ontario</li><li>État de São Paulo</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>São Paulo</li><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Avezum, Alvaro" sort="Avezum, Alvaro" uniqKey="Avezum A" first="Alvaro" last="Avezum">Alvaro Avezum</name><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name><name sortKey="Budaj, Andrzej" sort="Budaj, Andrzej" uniqKey="Budaj A" first="Andrzej" last="Budaj">Andrzej Budaj</name><name sortKey="Goodman, Shaun" sort="Goodman, Shaun" uniqKey="Goodman S" first="Shaun" last="Goodman">Shaun Goodman</name><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B." last="Granger">Christopher B. Granger</name><name sortKey="Jackson, Elizabeth A" sort="Jackson, Elizabeth A" uniqKey="Jackson E" first="Elizabeth A." last="Jackson">Elizabeth A. Jackson</name><name sortKey="Sadiq, Immad" sort="Sadiq, Immad" uniqKey="Sadiq I" first="Immad" last="Sadiq">Immad Sadiq</name><name sortKey="Steg, Philippe Gabriel" sort="Steg, Philippe Gabriel" uniqKey="Steg P" first="Philippe Gabriel" last="Steg">Philippe Gabriel Steg</name></noCountry><country name="États-Unis"><region name="Massachusetts"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></country><country name="France"><region name="Île-de-France"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="Pologne"><noRegion><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></noRegion></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="Canada"><region name="Ontario"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00B728 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00B728 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:02-0226463
|texte= Extent of, and factors associated with, delay to hospital presentation in patients with Acute Coronary disease (the GRACE registry)
}}
| This area was generated with Dilib version V0.6.33. |  |